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Population Stratification of a Common APOBEC Gene Deletion Polymorphism

The APOBEC3 gene family plays a role in innate cellular immunity inhibiting retroviral infection, hepatitis B virus propagation, and the retrotransposition of endogenous elements. We present a detailed sequence and population genetic analysis of a 29.5-kb common human deletion polymorphism that remo...

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Detalles Bibliográficos
Autores principales: Kidd, Jeffrey M, Newman, Tera L, Tuzun, Eray, Kaul, Rajinder, Eichler, Evan E
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1853121/
https://www.ncbi.nlm.nih.gov/pubmed/17447845
http://dx.doi.org/10.1371/journal.pgen.0030063