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Mechanism of chimera formation during the Multiple Displacement Amplification reaction

BACKGROUND: Multiple Displacement Amplification (MDA) is a method used for amplifying limiting DNA sources. The high molecular weight amplified DNA is ideal for DNA library construction. While this has enabled genomic sequencing from one or a few cells of unculturable microorganisms, the process is...

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Detalles Bibliográficos
Autores principales: Lasken, Roger S, Stockwell, Timothy B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855051/
https://www.ncbi.nlm.nih.gov/pubmed/17430586
http://dx.doi.org/10.1186/1472-6750-7-19