Adjuvant TACE inhibitor treatment improves the outcome of TLR2(-/- )mice with experimental pneumococcal meningitis

BACKGROUND: Streptococcus (S.) pneumoniae meningitis has a high lethality despite antibiotic treatment. Inflammation is a major pathogenetic factor, which is unresponsive to antibiotics. Therefore adjunctive therapies with antiinflammatory compounds have been developed. TNF484 is a TNF-alpha convert...

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Detalles Bibliográficos
Autores principales: Echchannaoui, Hakim, Leib, Stephen L, Neumann, Ulf, Landmann, Regine MA
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855056/
https://www.ncbi.nlm.nih.gov/pubmed/17428319
http://dx.doi.org/10.1186/1471-2334-7-25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855056/
https://www.ncbi.nlm.nih.gov/pubmed/17428319
http://dx.doi.org/10.1186/1471-2334-7-25

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