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Rapid detection of Pfcrt and Pfmdr1 mutations in Plasmodium falciparum isolates by FRET and in vivo response to chloroquine among children from Osogbo, Nigeria

BACKGROUND: Chloroquine (CQ) has been in use in Africa for a long time. Because of misuse, this drug has now lost its efficacy due to the emergence of resistance strains in most parts of Africa. Recently, it was shown that after chloroquine has been withdrawn from the market, chloroquine-sensitive P...

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Detalles Bibliográficos
Autores principales: Ojurongbe, Olusola, Ogungbamigbe, Titus O, Fagbenro-Beyioku, Adetayo F, Fendel, Rolf, Kremsner, Peter G, Kun, Jürgen FJ
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855061/
https://www.ncbi.nlm.nih.gov/pubmed/17428334
http://dx.doi.org/10.1186/1475-2875-6-41