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Combinatorial Computational Approaches to Identify Tetracycline Derivatives as Flavivirus Inhibitors
Limited structural information of drug targets, cellular toxicity possessed by lead compounds, and large amounts of potential leads are the major issues facing the design-oriented approach of discovering new leads. In an attempt to tackle these issues, we have developed a process of virtual screenin...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855430/ https://www.ncbi.nlm.nih.gov/pubmed/17502914 http://dx.doi.org/10.1371/journal.pone.0000428 |