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Glutamate-stimulated peroxynitrite production in a brain-derived endothelial cell line is dependent on N-methyl-d-aspartate (NMDA) receptor activation

There is accumulating and convincing evidence indicating a role for glutamate in the pathogenesis of the human demyelinating disease multiple sclerosis (MS). Studies in experimental autoimmune encephalomyelitis (EAE), the animal model of MS, demonstrate that pharmacological inhibition of specific gl...

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Detalles Bibliográficos
Autores principales: Scott, G.S., Bowman, S.R., Smith, T., Flower, R.J., Bolton, C.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855445/
https://www.ncbi.nlm.nih.gov/pubmed/17118345
http://dx.doi.org/10.1016/j.bcp.2006.09.021