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Mapping of possible prion protein self-interaction domains using peptide arrays
BACKGROUND: The common event in transmissible spongiform encephalopathies (TSEs) or prion diseases is the conversion of host-encoded protease sensitive cellular prion protein (PrP(C)) into strain dependent isoforms of scrapie associated protease resistant isoform (PrP(Sc)) of prion protein (PrP). Th...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855927/ https://www.ncbi.nlm.nih.gov/pubmed/17430579 http://dx.doi.org/10.1186/1471-2091-8-6 |