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Mapping of possible prion protein self-interaction domains using peptide arrays

BACKGROUND: The common event in transmissible spongiform encephalopathies (TSEs) or prion diseases is the conversion of host-encoded protease sensitive cellular prion protein (PrP(C)) into strain dependent isoforms of scrapie associated protease resistant isoform (PrP(Sc)) of prion protein (PrP). Th...

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Detalles Bibliográficos
Autores principales: Rigter, Alan, Langeveld, Jan PM, Timmers-Parohi, Drophatie, Jacobs, Jorg G, Moonen, Peter LJM, Bossers, Alex
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855927/
https://www.ncbi.nlm.nih.gov/pubmed/17430579
http://dx.doi.org/10.1186/1471-2091-8-6