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Ovarian cancer risk and common variation in the sex hormone-binding globulin gene: a population-based case-control study

BACKGROUND: The sex hormone-binding globulin (SHBG) is a carrier protein that modulates the bio-availability of serum sex steroid hormones, which may be involved in ovarian cancer. We evaluated whether common genetic variation in SHBG and its 3' neighbor ATP1B2, in linkage disequilibrium, is as...

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Detalles Bibliográficos
Autores principales: Garcia-Closas, Montserrat, Brinton, Louise A, Lissowska, Jolanta, Richesson, Douglas, Sherman, Mark E, Szeszenia-Dabrowska, Neonila, Peplonska, Beata, Welch, Robert, Yeager, Meredith, Zatonski, Witold, Chanock, Stephen J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855931/
https://www.ncbi.nlm.nih.gov/pubmed/17411440
http://dx.doi.org/10.1186/1471-2407-7-60