Generation of clinical grade dendritic cells with capacity to produce biologically active IL-12p70

BACKGROUND: For optimal T cell activation it is desirable that dendritic cells (DCs) display peptides within MHC molecules as signal 1, costimulatory molecules as signal 2 and, in addition, produce IL-12p70 as signal 3. IL-12p70 polarizes T cell responses towards CD4(+ )T helper 1 cells, which then...

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Detalles Bibliográficos
Autores principales: Zobywalski, Anke, Javorovic, Miran, Frankenberger, Bernhard, Pohla, Heike, Kremmer, Elisabeth, Bigalke, Iris, Schendel, Dolores J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1858682/
https://www.ncbi.nlm.nih.gov/pubmed/17430585
http://dx.doi.org/10.1186/1479-5876-5-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1858682/
https://www.ncbi.nlm.nih.gov/pubmed/17430585
http://dx.doi.org/10.1186/1479-5876-5-18

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