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Clofibrate treatment in pigs: Effects on parameters critical with respect to peroxisome proliferator-induced hepatocarcinogenesis in rodents

BACKGROUND: In rodents treatment with fibrates causes hepatocarcinogenesis, probably as a result of oxidative stress and an impaired balance between apoptosis and cell proliferation in the liver. There is some debate whether fibrates could also induce liver cancer in species not responsive to peroxi...

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Detalles Bibliográficos
Autores principales: Luci, Sebastian, Giemsa, Beatrice, Hause, Gerd, Kluge, Holger, Eder, Klaus
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1858689/
https://www.ncbi.nlm.nih.gov/pubmed/17437637
http://dx.doi.org/10.1186/1471-2210-7-6