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Conformational study of the protegrin-1 (PG-1) dimer interaction with lipid bilayers and its effect

BACKGROUND: Protegrin-1 (PG-1) is known as a potent antibiotic peptide; it prevents infection via an attack on the membrane surface of invading microorganisms. In the membrane, the peptide forms a pore/channel through oligomerization of multiple subunits. Recent experimental and computational studie...

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Detalles Bibliográficos
Autores principales: Jang, Hyunbum, Ma, Buyong, Nussinov, Ruth
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1858697/
https://www.ncbi.nlm.nih.gov/pubmed/17407565
http://dx.doi.org/10.1186/1472-6807-7-21