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Identification of a set of KSRP target transcripts upregulated by PI3K-AKT signaling

BACKGROUND: KSRP is a AU-rich element (ARE) binding protein that causes decay of select sets of transcripts in different cell types. We have recently described that phosphatidylinositol 3-kinase/AKT (PI3K-AKT) activation induces stabilization and accumulation of the labile β-catenin mRNA through an...

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Detalles Bibliográficos
Autores principales: Ruggiero, Tina, Trabucchi, Michele, Ponassi, Marco, Corte, Giorgio, Chen, Ching-Yi, al-Haj, Latifa, Khabar, Khalid SA, Briata, Paola, Gherzi, Roberto
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1858702/
https://www.ncbi.nlm.nih.gov/pubmed/17437629
http://dx.doi.org/10.1186/1471-2199-8-28