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A Helical Structural Nucleus Is the Primary Elongating Unit of Insulin Amyloid Fibrils
Although amyloid fibrillation is generally believed to be a nucleation-dependent process, the nuclei are largely structurally uncharacterized. This is in part due to the inherent experimental challenge associated with structural descriptions of individual components in a dynamic multi-component equi...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1858711/ https://www.ncbi.nlm.nih.gov/pubmed/17472440 http://dx.doi.org/10.1371/journal.pbio.0050134 |