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A Helical Structural Nucleus Is the Primary Elongating Unit of Insulin Amyloid Fibrils

Although amyloid fibrillation is generally believed to be a nucleation-dependent process, the nuclei are largely structurally uncharacterized. This is in part due to the inherent experimental challenge associated with structural descriptions of individual components in a dynamic multi-component equi...

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Detalles Bibliográficos
Autores principales:	Vestergaard, Bente, Groenning, Minna, Roessle, Manfred, Kastrup, Jette S, van de Weert, Marco, Flink, James M, Frokjaer, Sven, Gajhede, Michael, Svergun, Dmitri I
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1858711/ https://www.ncbi.nlm.nih.gov/pubmed/17472440 http://dx.doi.org/10.1371/journal.pbio.0050134

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