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Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel

Thermodynamic measurements of ion binding to the Streptomyces lividans K(+) channel were carried out using isothermal titration calorimetry, whereas atomic structures of ion-bound and ion-free conformations of the channel were characterized by x-ray crystallography. Here we use these assays to show...

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Detalles Bibliográficos
Autores principales: Lockless, Steve W, Zhou, Ming, MacKinnon, Roderick
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1858713/
https://www.ncbi.nlm.nih.gov/pubmed/17472437
http://dx.doi.org/10.1371/journal.pbio.0050121