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Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain
The etiology of osteoarthritis is multifactorial, with inflammatory, metabolic, and mechanical causes. Pain in osteoarthritis is initiated by mild intra-articular inflammation and degeneration of articular cartilage and subchondral bone. The principle of treatment with acetaminophen or non-steroidal...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860073/ https://www.ncbi.nlm.nih.gov/pubmed/17284318 http://dx.doi.org/10.1186/ar2121 |