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Expression, purification and characterization of recombinant severe acute respiratory syndrome coronavirus non-structural protein 1

The coronavirus (CoV) responsible for severe acute respiratory syndrome (SARS), SARS-CoV, encodes two large polyproteins (pp1a and pp1ab) that are processed by two viral proteases to yield mature non-structural proteins (nsps). Many of these nsps have essential roles in viral replication, but severa...

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Detalles Bibliográficos
Autores principales: Brucz, Kimberly, Miknis, Zachary J., Schultz, L. Wayne, Umland, Timothy C.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1862784/
https://www.ncbi.nlm.nih.gov/pubmed/17187987
http://dx.doi.org/10.1016/j.pep.2006.11.005