Protecting exons from deleterious R-loops: a potential advantage of having introns

BACKGROUND: Accumulating evidence indicates that the nascent RNA can invade and pair with one strand of DNA, forming an R-loop structure that threatens the stability of the genome. In addition, the cost and benefit of introns are still in debate. RESULTS: At least three factors are likely required f...

Descripción completa

Detalles Bibliográficos
Autor principal: Niu, Deng-Ke
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1863416/
https://www.ncbi.nlm.nih.gov/pubmed/17459149
http://dx.doi.org/10.1186/1745-6150-2-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1863416/
https://www.ncbi.nlm.nih.gov/pubmed/17459149
http://dx.doi.org/10.1186/1745-6150-2-11

Ejemplares similares