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Electron Tomography of the Contact between T Cells and SIV/HIV-1: Implications for Viral Entry

The envelope glycoproteins of primate lentiviruses, including human and simian immunodeficiency viruses (HIV and SIV), are heterodimers of a transmembrane glycoprotein (usually gp41), and a surface glycoprotein (gp120), which binds CD4 on target cells to initiate viral entry. We have used electron t...

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Detalles Bibliográficos
Autores principales: Sougrat, Rachid, Bartesaghi, Alberto, Lifson, Jeffrey D, Bennett, Adam E, Bess, Julian W, Zabransky, Daniel J, Subramaniam, Sriram
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1864992/
https://www.ncbi.nlm.nih.gov/pubmed/17480119
http://dx.doi.org/10.1371/journal.ppat.0030063