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DNA repair gene XRCC1 polymorphisms and bladder cancer risk

BACKGROUND: Cigarette smoking and chemical occupational exposure are the main known risk factors for bladder transitional cell carcinoma (TCC). Oxidative DNA damage induced by carcinogens present in these exposures requires accurate base excision repair (BER). The XRCC1 protein plays a crucial role...

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Detalles Bibliográficos
Autores principales: Sak, Sei Chung, Barrett, Jennifer H, Paul, Alan B, Bishop, D Timothy, Kiltie, Anne E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865553/
https://www.ncbi.nlm.nih.gov/pubmed/17425776
http://dx.doi.org/10.1186/1471-2156-8-13