Cargando…

A genome-scale computational study of the interplay between transcriptional regulation and metabolism

This paper presents a new method, steady-state regulatory flux balance analysis (SR-FBA), for predicting gene expression and metabolic fluxes in a large-scale integrated metabolic–regulatory model. Using SR-FBA to study the metabolism of Escherichia coli, we quantify the extent to which the differen...

Descripción completa

Detalles Bibliográficos
Autores principales: Shlomi, Tomer, Eisenberg, Yariv, Sharan, Roded, Ruppin, Eytan
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865583/
https://www.ncbi.nlm.nih.gov/pubmed/17437026
http://dx.doi.org/10.1038/msb4100141