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Drosophila SETDB1 Is Required for Chromosome 4 Silencing

Histone H3 lysine 9 (H3K9) methylation is associated with gene repression and heterochromatin formation. In Drosophila, SU(VAR)3–9 is responsible for H3K9 methylation mainly at pericentric heterochromatin. However, the histone methyltransferases responsible for H3K9 methylation at euchromatic sites,...

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Detalles Bibliográficos
Autores principales: Seum, Carole, Reo, Emanuela, Peng, Hongzhuang, Rauscher, Frank J, Spierer, Pierre, Bontron, Séverine
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866353/
https://www.ncbi.nlm.nih.gov/pubmed/17500594
http://dx.doi.org/10.1371/journal.pgen.0030076