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Binding Site Graphs: A New Graph Theoretical Framework for Prediction of Transcription Factor Binding Sites

Computational prediction of nucleotide binding specificity for transcription factors remains a fundamental and largely unsolved problem. Determination of binding positions is a prerequisite for research in gene regulation, a major mechanism controlling phenotypic diversity. Furthermore, an accurate...

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Detalles Bibliográficos
Autores principales: Reddy, Timothy E, DeLisi, Charles, Shakhnovich, Boris E
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866359/
https://www.ncbi.nlm.nih.gov/pubmed/17500587
http://dx.doi.org/10.1371/journal.pcbi.0030090