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A neural strategy for the inference of SH3 domain-peptide interaction specificity

BACKGROUND: The SH3 domain family is one of the most representative and widely studied cases of so-called Peptide Recognition Modules (PRM). The polyproline II motif PxxP that generally characterizes its ligands does not reflect the complex interaction spectrum of the over 1500 different SH3 domains...

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Detalles Bibliográficos
Autores principales: Ferraro, Enrico, Via, Allegra, Ausiello, Gabriele, Helmer-Citterich, Manuela
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866395/
https://www.ncbi.nlm.nih.gov/pubmed/16351739
http://dx.doi.org/10.1186/1471-2105-6-S4-S13