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A neural strategy for the inference of SH3 domain-peptide interaction specificity
BACKGROUND: The SH3 domain family is one of the most representative and widely studied cases of so-called Peptide Recognition Modules (PRM). The polyproline II motif PxxP that generally characterizes its ligands does not reflect the complex interaction spectrum of the over 1500 different SH3 domains...
Autores principales: | Ferraro, Enrico, Via, Allegra, Ausiello, Gabriele, Helmer-Citterich, Manuela |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866395/ https://www.ncbi.nlm.nih.gov/pubmed/16351739 http://dx.doi.org/10.1186/1471-2105-6-S4-S13 |
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