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Comparison of longitudinal variance components and regression-based approaches for linkage detection on chromosome 17 for systolic blood pressure

We compare two methods to detect genetic linkage by using serial observations of systolic blood pressure in pedigree data from the Framingham Heart Study focusing on chromosome 17. The first method is a variance components (VC) approach that incorporates longitudinal pedigree data, and the second me...

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Detalles Bibliográficos
Autores principales: Andrade, Mariza de, Olswold, Curtis
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866451/
https://www.ncbi.nlm.nih.gov/pubmed/14975085
http://dx.doi.org/10.1186/1471-2156-4-S1-S17