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Segregation and linkage analysis for longitudinal measurements of a quantitative trait

We present a method for using slopes and intercepts from a linear regression of a quantitative trait as outcomes in segregation and linkage analyses. We apply the method to the analysis of longitudinal systolic blood pressure (SBP) data from the Framingham Heart Study. A first-stage linear model was...

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Detalles Bibliográficos
Autores principales: Gee, Conway, Morrison, John L, Thomas, Duncan C, Gauderman, W James
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866456/
https://www.ncbi.nlm.nih.gov/pubmed/14975089
http://dx.doi.org/10.1186/1471-2156-4-S1-S21