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Genetic analyses of longitudinal phenotype data: a comparison of univariate methods and a multivariate approach

BACKGROUND: We explored three approaches to heritability and linkage analyses of longitudinal total cholesterol levels (CHOL) in the Genetic Analysis Workshop 13 simulated data without knowing the answers. The first two were univariate approaches and used 1) baseline measure at exam one or 2) summar...

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Detalles Bibliográficos
Autores principales: Yang, Qiong, Chazaro, Irmarie, Cui, Jing, Guo, Chao-Yu, Demissie, Serkalem, Larson, Martin, Atwood, Larry D, Cupples, L Adrienne, DeStefano, Anita L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866464/
https://www.ncbi.nlm.nih.gov/pubmed/14975097
http://dx.doi.org/10.1186/1471-2156-4-S1-S29