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Comparison of significance level at the true location using two linkage approaches: LODPAL and GENEFINDER

BACKGROUND: We compare two new software packages for linkage analysis, LODPAL and GENEFINDER. Both allow for covariate adjustment. Replicates 1 to 3 of Genetic Analysis Workshop 13 simulated data sets were used for the analyses. We described the results of searching for evidence of loci contributing...

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Detalles Bibliográficos
Autores principales: Hsu, Fang-Chi, Hetmanski, Jacqueline B, Li, Lan, Markakis, Diane, Jacobs, Kevin, Shugart, Yin Yao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866482/
https://www.ncbi.nlm.nih.gov/pubmed/14975114
http://dx.doi.org/10.1186/1471-2156-4-S1-S46