Cargando…

Transmission ratio distortion in families from the Framingham Heart Study

BACKGROUND: One implicit assumption in most linkage analysis is that live-born siblings unselected for a phenotype do not share alleles greater than the Mendelian expectation at any particular locus. However, since most families are recruited for genetic studies because of the presence of disease, t...

Descripción completa

Detalles Bibliográficos
Autores principales: Paterson, Andrew D, Sun, Lei, Liu, Xiao-Qing
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866484/
https://www.ncbi.nlm.nih.gov/pubmed/14975116
http://dx.doi.org/10.1186/1471-2156-4-S1-S48