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A statistical method for adjusting covariates in linkage analysis with sib pairs

BACKGROUND: We propose a statistical method that includes the use of longitudinal regression models and estimation procedures for adjusting for covariate effects in applying the Haseman-Elston (HE) method for linkage analysis. Our methodology, which uses the covariate adjusted trait, contains three...

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Detalles Bibliográficos
Autores principales: Wu, Colin O, Zheng, Gang, Leifer, Eric, Follmann, Dean, Lin, Jing-Ping
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866488/
https://www.ncbi.nlm.nih.gov/pubmed/14975119
http://dx.doi.org/10.1186/1471-2156-4-S1-S51