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Mapping loci influencing blood pressure in the Framingham pedigrees using model-free LOD score analysis of a quantitative trait

This paper presents a method of performing model-free LOD-score based linkage analysis on quantitative traits. It is implemented in the QMFLINK program. The method is used to perform a genome screen on the Framingham Heart Study data. A number of markers that show some support for linkage in our stu...

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Detalles Bibliográficos
Autores principales: Knight, Jo, North, Bernard V, Sham, Pak C, Curtis, David
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866513/
https://www.ncbi.nlm.nih.gov/pubmed/14975142
http://dx.doi.org/10.1186/1471-2156-4-S1-S74