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Segregation analysis comparing liability and quantitative trait models for hypertension using the Genetic Analysis Workshop 13 simulated data

Discrete (qualitative) data segregation analysis may be performed assuming the liability model, which involves an underlying normally distributed quantitative phenotype. The appropriateness of the liability model for complex traits is unclear. The Genetic Analysis Workshop 13 simulated data provides...

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Detalles Bibliográficos
Autores principales: Crockford, GP, Bishop, DT, Barrett, JH
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866518/
https://www.ncbi.nlm.nih.gov/pubmed/14975147
http://dx.doi.org/10.1186/1471-2156-4-S1-S79