Using an age-at-onset phenotype with interval censoring to compare methods of segregation and linkage analysis in a candidate region for elevated systolic blood pressure

BACKGROUND: Genetic studies of complex disorders such as hypertension often utilize families selected for this outcome, usually with information obtained at a single time point. Since age-at-onset for diagnosed hypertension can vary substantially between individuals, a phenotype based on long-term f...

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Detalles Bibliográficos
Autores principales: Kopciuk, Karen A, Briollais, Laurent, Demenais, Florence, Bull, Shelley B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866524/
https://www.ncbi.nlm.nih.gov/pubmed/14975152
http://dx.doi.org/10.1186/1471-2156-4-S1-S84

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866524/
https://www.ncbi.nlm.nih.gov/pubmed/14975152
http://dx.doi.org/10.1186/1471-2156-4-S1-S84

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