Comparison of linkage analysis methods for genome-wide scanning of extended pedigrees, with application to the TG/HDL-C ratio in the Framingham Heart Study

BACKGROUND: High triglycerides (TG) and low high-density lipoprotein cholesterol (HDL-C) jointly increase coronary disease risk. We performed linkage analysis for TG/HDL-C ratio in the Framingham Heart Study data as a quantitative trait, using methods implemented in LINKAGE, GENEHUNTER (GH), MCLINK,...

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Detalles Bibliográficos
Autores principales: Horne, Benjamin D, Malhotra, Alka, Camp, Nicola J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866534/
https://www.ncbi.nlm.nih.gov/pubmed/14975161
http://dx.doi.org/10.1186/1471-2156-4-S1-S93

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866534/
https://www.ncbi.nlm.nih.gov/pubmed/14975161
http://dx.doi.org/10.1186/1471-2156-4-S1-S93

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