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Identifying genetic variation affecting a complex trait in simulated data: a comparison of meta-analysis with pooled data analysis

We explored the power and consistency to detect linkage and association with meta-analysis and pooled data analysis using Genetic Analysis Workshop 14 simulated data. The first 10 replicates from Aipotu population were used. Significant linkage and association was found at all 4 regions containing t...

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Detalles Bibliográficos
Autores principales: Wu, Xiaodong, Kan, Donghui, Cooper, Richard S, Zhu, Xiaofeng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866682/
https://www.ncbi.nlm.nih.gov/pubmed/16451713
http://dx.doi.org/10.1186/1471-2156-6-S1-S97