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Impact of non-ignorable missingness on genetic tests of linkage and/or association using case-parent trios
The transmission/disequilibrium test was introduced to test for linkage disequilibrium between a marker and a putative disease locus using case-parent trios. However, parental genotypes may be incomplete in such a study. When parental information is non-randomly missing, due, for example, to death f...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866689/ https://www.ncbi.nlm.nih.gov/pubmed/16451706 http://dx.doi.org/10.1186/1471-2156-6-S1-S90 |