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Impact of non-ignorable missingness on genetic tests of linkage and/or association using case-parent trios

The transmission/disequilibrium test was introduced to test for linkage disequilibrium between a marker and a putative disease locus using case-parent trios. However, parental genotypes may be incomplete in such a study. When parental information is non-randomly missing, due, for example, to death f...

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Detalles Bibliográficos
Autores principales: Guo, Chao-Yu, Cui, Jing, Cupples, L Adrienne
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866689/
https://www.ncbi.nlm.nih.gov/pubmed/16451706
http://dx.doi.org/10.1186/1471-2156-6-S1-S90

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