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Fine-scale mapping in case-control samples using locus scoring and haplotype-sharing methods

Both haplotype-based and locus-based methods have been proposed as the most powerful methods to employ when fine mapping by association. Although haplotype-based methods utilize more information, they may lose power as a result of overparameterization, given the large number of haplotypes possible o...

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Detalles Bibliográficos
Autores principales: Humphreys, Keith, Iles, Mark M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866707/
https://www.ncbi.nlm.nih.gov/pubmed/16451688
http://dx.doi.org/10.1186/1471-2156-6-S1-S74