Strategies for selecting subsets of single-nucleotide polymorphisms to genotype in association studies

In genetic association studies, linkage disequilibrium (LD) within a region can be exploited to select a subset of single-nucleotide polymorphisms (SNPs) to genotype with minimal loss of information. A novel entropy-based method for selecting SNPs is proposed and compared to an existing method based...

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Detalles Bibliográficos
Autores principales: Butler, Joe M, Bishop, D Timothy, Barrett, Jennifer H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866709/
https://www.ncbi.nlm.nih.gov/pubmed/16451686
http://dx.doi.org/10.1186/1471-2156-6-S1-S72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866709/
https://www.ncbi.nlm.nih.gov/pubmed/16451686
http://dx.doi.org/10.1186/1471-2156-6-S1-S72

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