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Haplotype-sharing analysis using Mantel statistics for combined genetic effects

We applied a new approach based on Mantel statistics to analyze the Genetic Analysis Workshop 14 simulated data with prior knowledge of the answers. The method was developed in order to improve the power of a haplotype sharing analysis for gene mapping in complex disease. The new statistic correlate...

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Detalles Bibliográficos
Autores principales: Beckmann, Lars, Fischer, Christine, Obreiter, Markus, Rabes, Michael, Chang-Claude, Jenny
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866711/
https://www.ncbi.nlm.nih.gov/pubmed/16451684
http://dx.doi.org/10.1186/1471-2156-6-S1-S70