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Fine-mapping using the weighted average method for a case-control study

We present a new method for fine-mapping a disease susceptibility locus using a case-control design. The new method, termed the weighted average (WA) statistic, averages the Cochran-Armitage (CA) trend test statistic and the difference between the Hardy-Weinberg disequilibrium test statistic for cas...

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Detalles Bibliográficos
Autores principales: Song, Kijoung, Orloff, Mohammed S, Lu, Qing, Elston, Robert C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866715/
https://www.ncbi.nlm.nih.gov/pubmed/16451680
http://dx.doi.org/10.1186/1471-2156-6-S1-S67