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Comparison of family-based association tests in chromosome regions selected by linkage-based confidence intervals

We use the Genetic Analysis Workshop 14 simulated data to explore the effectiveness of a two-stage strategy for mapping complex disease loci consisting of an initial genome scan with confidence interval construction for gene location, followed by fine mapping with family-based tests of association o...

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Detalles Bibliográficos
Autores principales: Lewinger, Juan Pablo, Lee, Sophia SF, Biernacka, Joanna, Wu, Long Yang, Shi, Haijiang Steven, Bull, Shelley B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866720/
https://www.ncbi.nlm.nih.gov/pubmed/16451675
http://dx.doi.org/10.1186/1471-2156-6-S1-S62