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The effect of linkage disequilibrium on linkage analysis of incomplete pedigrees
Dense SNP maps can be highly informative for linkage studies. But when parental genotypes are missing, multipoint linkage scores can be inflated in regions with substantial marker-marker linkage disequilibrium (LD). Such regions were observed in the Affymetrix SNP genotypes for the Genetic Analysis...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866723/ https://www.ncbi.nlm.nih.gov/pubmed/16451672 http://dx.doi.org/10.1186/1471-2156-6-S1-S6 |