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The effect of linkage disequilibrium on linkage analysis of incomplete pedigrees

Dense SNP maps can be highly informative for linkage studies. But when parental genotypes are missing, multipoint linkage scores can be inflated in regions with substantial marker-marker linkage disequilibrium (LD). Such regions were observed in the Affymetrix SNP genotypes for the Genetic Analysis...

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Detalles Bibliográficos
Autores principales:	Levinson, Douglas F, Holmans, Peter
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866723/ https://www.ncbi.nlm.nih.gov/pubmed/16451672 http://dx.doi.org/10.1186/1471-2156-6-S1-S6

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