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Critical values and variation in type I error along chromosomes in the COGA dataset using the applied pseudo-trait method

BACKGROUND: By analyzing a "pseudo-trait," a trait not linked or associated with any of the markers tested, the distribution of the test statistic under the null hypothesis can provide the critical value for the appropriate percentile of the distribution. In addition, the anecdotal observa...

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Detalles Bibliográficos
Autores principales: Papanicolaou, George J, Justice, Cristina M, Kovac, Illija M, Sorant, Alexa JM, Wilson, Alexander F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866729/
https://www.ncbi.nlm.nih.gov/pubmed/16451666
http://dx.doi.org/10.1186/1471-2156-6-S1-S54