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Linkage analysis of alcohol dependence using both affected and discordant sib pairs

The basic idea of affected-sib-pair (ASP) linkage analysis is to test whether the inheritance pattern of a marker deviates from Mendelian expectation in a sample of ASPs. The test depends on an assumed Mendelian control distribution of the number of marker alleles shared identical by descent (IBD),...

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Detalles Bibliográficos
Autores principales: Shih, Pei-Ying, Wang, Tao, Xing, Chao, Sinha, Moumita, Song, Yeunjoo, Elston, Robert C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866749/
https://www.ncbi.nlm.nih.gov/pubmed/16451646
http://dx.doi.org/10.1186/1471-2156-6-S1-S36