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Linkage analysis of alcohol dependence using both affected and discordant sib pairs

The basic idea of affected-sib-pair (ASP) linkage analysis is to test whether the inheritance pattern of a marker deviates from Mendelian expectation in a sample of ASPs. The test depends on an assumed Mendelian control distribution of the number of marker alleles shared identical by descent (IBD),...

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Detalles Bibliográficos
Autores principales:	Shih, Pei-Ying, Wang, Tao, Xing, Chao, Sinha, Moumita, Song, Yeunjoo, Elston, Robert C
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866749/ https://www.ncbi.nlm.nih.gov/pubmed/16451646 http://dx.doi.org/10.1186/1471-2156-6-S1-S36

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