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Resampling methods to reduce the selection bias in genetic effect estimation in genome-wide scans

Using the simulated data of Problem 2 for Genetic Analysis Workshop 14 (GAW14), we investigated the ability of three bootstrap-based resampling estimators (a shrinkage, an out-of-sample, and a weighted estimator) to reduce the selection bias for genetic effect estimation in genome-wide linkage scans...

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Detalles Bibliográficos
Autores principales: Wu, Long Yang, Lee, Sophia SF, Shi, Haijiang Steven, Sun, Lei, Bull, Shelley B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866762/
https://www.ncbi.nlm.nih.gov/pubmed/16451633
http://dx.doi.org/10.1186/1471-2156-6-S1-S24