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Inclusion of unaffected sibs increases power in model-free linkage analysis of a behavioral trait

Study design strategies are of critical importance in the search for genes underlying complex diseases. Two important design choices in planning gene mapping studies are the analytic strategy to be used, which will have an impact on the type of data to be collected, and the choice of genetic markers...

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Detalles Bibliográficos
Autores principales: Plancoulaine, Sabine, Alcaïs, Alexandre, Chen, Yue, Abel, Laurent, Gagnon, France
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866764/
https://www.ncbi.nlm.nih.gov/pubmed/16451631
http://dx.doi.org/10.1186/1471-2156-6-S1-S22